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Vaccination: Vaccines
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Total 294 results found since Jan 2013.
The prevalence and clinical course of shoulder injury related to vaccine administration (SIRVA) after COVID-19 vaccines in Dutch hospital workers
CONCLUSIONS: The prevalence of SIRVA is estimated at 3% in the adult working population. Signs and symptoms of SIRVA are variable in severity, localization and timing. Soft-tissue abnormalities is the most common clinical sign. This study contributes to clinician's knowledge on SIRVA, aiding in early recognition and treatment, which are imperative for prevention of persistent and severe shoulder pathology.PMID:37635003 | DOI:10.1016/j.vaccine.2023.08.043
Source: Vaccine - August 27, 2023 Category: Allergy & Immunology Authors: Esther R C Janssen Astrid Z van Montfoort Freek Hollman Frederik O Lambers Heerspink Source Type: research
Vaccination against Extracellular Vimentin for Treatment of Urothelial Cancer of the Bladder in Client-Owned Dogs
Cancers (Basel). 2023 Aug 3;15(15):3958. doi: 10.3390/cancers15153958.ABSTRACTIt was recently shown that targeting extracellular vimentin (eVim) is safe and effective in preclinical models. Here, we report the safety and efficacy in client-owned dogs with spontaneous bladder cancer of CVx1, an iBoost technology-based vaccine targeting eVim in combination with COX-2 inhibition. This was a single-arm prospective phase 1/2 study with CVx1 in 20 client-owned dogs with spontaneous UC which involved four subcutaneous vaccinations with CVx1 at 2-week intervals for induction of antibody titers, followed by maintenance vaccinations...
Source: Cancer Control - August 12, 2023 Category: Cancer & Oncology Authors: Diederik J M Engbersen Judy R van Beijnum Arno Roos Marit van Beelen Jan David de Haan Guy C M Grinwis Jack A Schalken J Alfred Witjes Arjan W Griffioen Elisabeth J M Huijbers Source Type: research
Age-dependent modulation of gut microbiome in response to tumor immunomodulation
In this study, we sequentially treated young mice (~8 weeks) and old mice (>18 months) with bilateral melanoma using FUS and calreticulin nanoparticles (CRT-NP) to enhance immunogenic cell death. The combination of CRT-NP and FUS (CFUS) demonstrated greater efficacy in inducing regression of treated and untreated tumors in young mice compared to old mice. The diminished effectiveness in older mice was associated with significant differences in gut microbiome composition, characterized by alterations in bacterial species and splenic immune cells. Specifically, young mice exposed to CFUS exhibited higher abundance of Bact...
Source: Experimental Gerontology - August 12, 2023 Category: Geriatrics Authors: Akansha Singh Harshini Ashar Ashish Ranjan Source Type: research
The most common gastrointestinal alterations in patients with post-COVID syndrome
CONCLUSION: We identified female gender, obesity, cardiovascular diseases, cancer, hypertension and diabetes as major risk factors of post-COVID syndrome. Vaccinated status may prevent post-COVID gastrointestinal symptoms. Orv Hetil. 2023; 164(31): 1206-1212.PMID:37543972 | DOI:10.1556/650.2023.32839
Source: Orvosi Hetilap - August 6, 2023 Category: General Medicine Authors: Kata Angyal Anna Mandula Tajthy B álint Drácz P ál Miheller Mikl ós Horváth Hajnal Sz ékely Veronika Papp Di ána Czompa Attila Szij ártó Kl ára Werling Source Type: research
Assessing importance of SARS-CoV2 infection as cause of in utero fetal death: regional retrospective cohort study
CONCLUSIONS: At the height of the SARS-CoV2 pandemic, more than half of the causes of fetal death in the Paris area were labeled placental or undetermined origin based on postmortem findings, but our study showed that, of these causes, 2.8% were due to placental SARS-CoV2 infection with a specific pattern of histological involvement. This study highlights the need for SARS-CoV2 screening in stillbirth assessment. The impact of vaccination coverage remains to be established. This article is protected by copyright. All rights reserved.PMID:37519281 | DOI:10.1002/uog.27439
Source: The Ultrasound Review of Obstetrics and Gynecology - July 31, 2023 Category: Radiology Authors: M Nkobetchou M Leruez-Ville T Guilleminot N Roux G Petrilli F Guimiot M-H Saint-Frison I Deryabin Y Ville V Faure Bardon Source Type: research
